Diazepam and Metabolite

Test Code

90853

CPT Codes
80346

Includes

Diazepam, Nordiazepam, Diazepam and Nordiazepam

Preferred Specimen

2 mL serum collected in a red-top tube (no gel)

Patient Preparation
Collect at trough concentration, i.e., immediately before the administration of the next dose

Minimum Volume

1 mL

Instructions

Use polypropylene tubes

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 5 days
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum Separator Tube (SST®)

Methodology
Calculation (CALC) • Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues, Thurs, Sat; Report available: 2-4 days

Clinical Significance

Therapeutic drug monitoring of anxiolytic drug. Nordiazepam is the active metabolite of the parent drug. Elimination half-life is 20-90 hours.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.