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Hydrocodone and Metabolite, Serum
Test Code90489
CPT Codes
80361 (HCPCS: G0480)
Includes
Hydrocodone, Free and Hydromorphone, Free
Preferred Specimen
5 mL serum collected in a red-top tube (no gel)
Minimum Volume
2.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 14 days
Refrigerated: 14 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
A.M. Sets up 2 days a week.
Clinical Significance
Therapeutic drug monitoring and confirmation of screen- positive results. Hydrocodone is an active component of Vicodin®, Lorcet®, Lortab®, etc. Serum half-life is 3.4 to 8.8 hours. Hydromorphone is an active ingredient in Dilaudid®. Serum half-life is 1.5 to 3.8 hours.
