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Fluoxetine
Test Code8389
CPT Codes
80299
Includes
Norfluoxetine, Fluoxetine and Total
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube or lithium heparin (green-top) tube
Instructions
Do not use gel barrier/serum separator tubes
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 5 days
Frozen: 30 days
Refrigerated: 5 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Sat; Report available: 2-5 days
Clinical Significance
Fluoxetine is an antidepressant drug that is also used in the treatment of bulimia nervosa and obsessive-compulsive disorder. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.