Tacrolimus and Sirolimus, LC/MS/MS

Test Code

70006

CPT Codes
80195, 80197 <br><strong>This test is not available for New York patient testing. For New York patient testing use test code 13607.</strong>

Preferred Specimen

4 mL whole blood collected in an EDTA (lavender-top) tube

Patient Preparation
Collect specimen 1 hour prior to next dose (12 hour trough)

Minimum Volume

2 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Clotted specimen

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

See individual assays

Clinical Significance

Tacrolimus (FK506) and Sirolimus (Rapamycin) are immunosuppressive drugs used in organ transplantation to prevent graft rejection. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.