Trazodone, Serum (4732X)

Test Code

40642P

CPT Codes
80299

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube

Instructions

Serum separator tubes are unacceptable

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 60 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gel barrier/serum separator tube

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues, Sat; Report available: 2-5 days

Clinical Significance

For therapeutic drug monitoring of antidepressant therapy. Peak plasma levels occur approximately 1 hour after dosing when Trazodone is taken on an empty stomach or 2 hours after dosing when taken with food. Elimination of Trazodone is biphasic, consisting of an initial phase (half-life 3-6 hours) followed by a slower phase (half-life 5-9 hours).

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.