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Ceruloplasmin
Test Code326
CPT Codes
82390
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 8 days
Refrigerated: 14 days
Frozen: 90 days
Refrigerated: 14 days
Frozen: 90 days
Methodology
Immunoturbidimetric Assay
Setup Schedule
Set up: Mon-Sat; Report available: Next day
Clinical Significance
Decreased levels of ceruloplasmin are found in Wilson's Disease, fulminant liver failure, intestinal malabsorption, renal failure resulting in proteinuria, chronic active hepatitis and malnutrition. Elevated levels are found in primary biliary cirrhosis, pregnancy (first trimester), oral contraceptive use and in acute inflammatory conditions since ceruloplasmin is an acute phase reactant.
