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Aluminum
Test Code2958
CPT Codes
82108
Preferred Specimen
2 mL serum collected in a no additive (royal blue-top) trace element tube
Minimum Volume
0.7 mL
Other Acceptable Specimens
Plasma collected in: EDTA (royal blue-top) tube or sodium heparin (royal blue-top) tube
Instructions
Draw one (royal blue-top) tube of blood and discard. Draw second (royal-blue top) tube. Allow to clot in an upright position. Centrifuge and pour (do not pipette) the serum or plasma into an acid-washed or metal-free vial.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
Setup Schedule
P.M.
Limitations
This measure is very sensitive to aluminum containing medications, e.g., aluminum-containing antacids, and may continue to test as elevated for a prolonged period of time after the medication is stopped.
Clinical Significance
Individuals undergoing hemodialysis are at risk for aluminum toxicity. Prolonged accumulation may cause anemia, encephalopathy, and vitamin D-resistant osteomalacia. Also, workers exposed to high levels or to long-term low levels of aluminum dust are at increased risk of toxicity.
