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Benzodiazepines, Serum
Test Code70071X
CPT Codes
<font face="Arial">80346</font>
Includes
Alprazolam, Alpha-Hydroxyalprazolam, Alpha-Hydroxytriazolam, Chlordiazepoxide, Clonazepam, Desalkylflurazepam, Diazepam, Lorazepam, Midazolam, Norchlordiazepoxide, Nordiazepam, Oxazepam, Temazepam, Triazolam
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: 14 days
Refrigerated: 72 hours
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gel barrier/Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
A.M.
Clinical Significance
Benzodiazepines are widely used as anxiolytics, sedative- hypnotics, muscle relaxants, and anticonvulsants. Benzodiazepines include drugs such as diazepam Valium®, chlordiazepoxide Librium®, oxazepam Serax®, lorazepam Ativan®, alprazolam Xanax®, clonazepam Clonopin® and triazolam Halcion®. Many common benzodiazepines are detected in urine by their metabolites oxazepam and nordiazepam. Psychological and physiological addictions, misuse and abuse of benzodiazepines have been described.
