Adenosine Deaminase, RBC

Test Code

39148

CPT Codes
82657<br /> <strong>This test is not available for New York patient testing.</strong> <br /> Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Preferred Specimen

1 mL whole blood collected in an EDTA (lavender-top or pink-top) or sodium or lithium heparin (green top) tube

Minimum Volume

1 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 15 days
Refrigerated: 15 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Frozen

Methodology
Kinetic Spectrophotometry

Setup Schedule

Sets up 3 days a week.

Report Available

Reports in 1 to 4 days.

Clinical Significance

Adenosine Deaminase (ADA) deficiency is an autosomal recessive disorder of purine metabolism primarily affecting lymphocyte development, viability, and function. Affected individuals have less than 1 percent of normal ADA catalytic activity in red cell hemolysates. ADA deficiency is the cause of 20-30 percent of SCID cases. If the patient has been recently transfused, ADA deficiency may be masked; interpret results with caution. Heterozygotes cannot be identified by this test.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.