Tick-Borne Disease, Antibody Panel

Test Code

36942

CPT Codes
86666 (x2), 86753 (x3), 86618, 86666 (x2)

Includes

Anaplasma phagocytophilum Antibodies (IgG, IgM)
WA1 IgG Antibody, IFA
Babesia microti Antibodies (IgG, IgM), IFA
Lyme Disease Ab with Reflex to Blot (IgG, IgM)
Ehrlichia chaffeensis (IgG, IgM)

If Lyme Disease Antibody Screen is ≥0.90, then Lyme Disease Antibodies (IgG, IgM), Immunoblot will be performed at an additional charge (CPT code(s): 86617 x2).

Preferred Specimen

2 mL serum

Minimum Volume

1.5 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology
See individual tests

FDA Status
Anaplasma phagocytophilum Antibodies (IgG, IgM), Babesia microti Antibodies (IgG, IgM), and Ehrlichia chaffeensis (IgG, IgM): This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Sets up 5 days a week.

Clinical Significance

There is substantial clinical overlap among tick-borne diseases caused by Anaplasma, Babesia, Borrelia, and Ehrlichia. Some infections can progress to severe complications such as anemia, hepatitis and pneumonia.. More than one infectious agent may be transmitted by the same tick, and rates of co-infection are not well defined since clinicians may only suspect a single tick-borne disease etiology.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.