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Zinc Protoporphyrin (ZPP)
Test Code948
CPT Codes
84202
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube - protect from light
Minimum Volume
0.5 mL
Other Acceptable Specimens
Light protected whole blood collected in: EDTA (royal blue-top) tube • Sodium heparin (green-top) tube • Sodium heparin lead-free (tan-top) tube • EDTA K2 (tan-top) tube
Instructions
Use lead-free tube if blood lead is also requested. Specimen should be foil wrapped. Protect from light.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 10 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Received frozen • Clotted
Methodology
Hematofluorometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available 1 days
Limitations
Aluminum and anemia of chronic disease may cause elevated results.
Clinical Significance
Zinc protoporphyrin (ZPP) accumulates in erythrocytes as a result of chronic lead absorption or iron deficiency anemia.