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Acetylcholinesterase
Test Code4929
CPT Codes
82664<br>**This test is not available for New York patient testing. For New York patient testing, use test code 10230.**
Preferred Specimen
1.5 mL amniotic fluid collected in a sterile transport tube
Minimum Volume
0.5 mL
Instructions
Collect in sterile transport tube. Indicate gestational age, collection date, clinical indication, and the AFP and MoM results if available, on the request form.
Note: This test is automatically performed on all Alpha-Fetoprotein amniotic fluids when the MoM is greater than 1.99.
Note: This test is automatically performed on all Alpha-Fetoprotein amniotic fluids when the MoM is greater than 1.99.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Rrefrigerated: 4 months
Frozen: 3 years
Rrefrigerated: 4 months
Frozen: 3 years
Methodology
Gel Electrophoresis
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon, Wed, Fri; Report available: 2-5 days
Limitations
Substantial hemorrhage into amniotic fluid may cause AChE and AFP to increase.
Clinical Significance
Acetylcholinesterase is useful to confirm fetal open neural tube defects and open ventral abdominal wall defects. Hemoglobin F, amniotic fluid is typically ordered simultaneously to exclude the possibility of fetal blood contamination.