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Penta Screen
Test Code15934
CPT Codes
81512<br /> **Not for California Clients. For New York patient testing, use test code 16970**
Includes
AFP, unconjugated Estriol, hCG, Dimeric Inhibin A, ITA (hyperglycosylated hCG) and Maternal Risk Interpretation
Preferred Specimen
4 mL serum
Minimum Volume
1.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 28 days
Refrigerated: 14 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
A.M. Sets up 6 days a week.
Limitations
Penta Screen results consistent with an increased risk of trisomy should be confirmed with amniotic fluid specimen. Results consistent with increased risk of NTD may be followed-up with appropriate diagnostic testing as detailed in the report. Maternal serum screening yields a low percentage of false negatives. A wide range of other chromosomal abnormalities are not identified by maternal serum screening.
Clinical Significance
To screen a woman in her second trimester of pregnancy for Neural Tube Defects, Down Syndrome and Trisomy 18 at 9 to 13 weeks gestation.
