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Vancomycin, Peak and Trough
Test Code5406
CPT Codes
80202 (x2)
Preferred Specimen
1 mL serum collected in each of two separate red-top tubes (no gel)
Patient Preparation
Collect peak 1 hour after completion of the drug infusion. Collect as a trough just prior to next dose.
Minimum Volume
0.2 mL for each specimen
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, lithium heparin (green-top) tube or fuoride/oxalate (gray-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: Unacceptable
Refrigerated: 7 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)
Methodology
Immunoassay (IA)
Setup Schedule
See individual assays
Clinical Significance
Vancomycin is an antibiotic used in the treatment of bacterial infections, especially methicillin-resistant staphylococci. Vancomycin is also used in treatment for penicillin-allergic patients who cannot receive or have failed to respond to other drugs, including the penicillins and/or cephalosporins and for other infections caused by vancomycin-susceptible organisms.