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DPPX Receptor Antibody, CBA IFA
Test Code93891
CPT Codes
86255
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel) or CSF collected in a sterile screw-cap container
Minimum Volume
0.3 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST)
Methodology
Cell Binding Assay-Immunofluorescence Assay (CBA-IFA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Sets up 2 days a week.
Clinical Significance
Dipeptidyl peptidase-like protein 6 (DPPX) is a regulatory subunit of voltage gated potassium channels in neurons of the central nervous system. Antibodies to DPPX have been associated with agitation, confusion, amnesia, delirium, allodynia, myoclonus, rigidity, tremor, exaggerated startle, ataxia, dysphagia, dysarthria seizures, psychosis, depression, sleep disturbance, respiratory failure and unexplained diarrhea, gastroparesis constipation, bladder dysautonomia, and abnormalities in cardiac conduction and thermoregulation.
