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Interleukin-2 Receptor Alpha Chain (IL-2Ra/CD25), Soluble
Test Code34298
CPT Codes
83520
Preferred Specimen
1 mL frozen serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Instructions
IL-2R levels may demonstrate diurnal variation. Recommend IL-2R levels be determined at the same time of day for improved longitudinal comparison.
No biotin supplements 48 hours prior to blood draw.
No biotin supplements 48 hours prior to blood draw.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen: 30 days
Refrigerated: 24 hours
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST) • Plasma • Received room temperature • Received refrigerated
Methodology
Immunoassay (IA)
FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Setup Schedule
Night Sets up 1 day a week.
Clinical Significance
Following stimulation by antigen, IL-2R is expressed on all T cells. IL-2R is released by activated cells into the surrounding extracellular fluid. IL2-R is involved in infectious, inflammatory and autoimmune diseases, cancer, and transplantation. IL-2R Antibodies are used therapeutically.
