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Delta Aminolevulinic Acid, Random Urine
Test Code6301
CPT Codes
82135
Preferred Specimen
2 mL random urine collected in sterile leak-proof container - protected from light
Minimum Volume
0.6 mL
Other Acceptable Specimens
Urine preserved with 1 mL concentrated glacial acetic acid or 1 mL 6N HCl, protected from light, catherized urine in sterile, plastic, screw-capped container
Instructions
Wrap container in alumuninum foil to protect from light. Do not use preservatives.
Do not use first morning void, late evening specimen (after 8 p.m.), or specimen after excessive fluid intake. Keep refrigerated and transport refrigerated (cold packs).
Do not use first morning void, late evening specimen (after 8 p.m.), or specimen after excessive fluid intake. Keep refrigerated and transport refrigerated (cold packs).
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Not protected from light
Methodology
Colorimetric (C)
Setup Schedule
P.M.
Clinical Significance
ALA is a precursor to uroporphyrin, coproporphyrin, and protoporphyrin. Concentrations of ALA are greatly increased in many patients with acute neurological forms of porphyrias and in some patients with chronic alcohol abuse.