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Apolipoprotein E (APOE) Isoform, CSF
Test Code94626
CPT Codes
82542<br /> ** This test is not available for New York patient testing **
Preferred Specimen
0.4 mL CSF collected in a polypropylene tube
Minimum Volume
0.2 mL
Instructions
Collect and transport CSF in a 12x75 mm polypropylene tube. Store frozen.
Note: Quest Diagnostics does not perform this test for individuals under the age of 18. Pre-test and post-test counseling is strongly recommended.
Transport Temperature
Frozen
Specimen Stability
Room tempurature: 72 hours
Refrigerated: 5 days
Frozen: 31 days
Refrigerated: 5 days
Frozen: 31 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Grossly lipemic • Specimen collected in a glass, polystyrene, or polycarbonate tube • Moderately or grossly icteric
Methodology
Liquid Chromotography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Night
Clinical Significance
This LC-MS/MS assay identifies the ApoE isoform(s) in CSF. This information can aid in assessing likelihood of AD.