CASPR2 Antibody Test

Test Code
92413


CPT Codes
86255

Preferred Specimen
2 mL serum


Minimum Volume
0.5 mL


Other Acceptable Specimens
CSF collected in: Sterile leak-proof container


Instructions
Serum must be separated from whole blood within 48 hours of collection.

Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Turbid • Bacterial contamination


Methodology
Immunofluorescence Assay (IFA)

Setup Schedule
Sets up 3 days a week.


Clinical Significance
Anti-CASPR2 antibodies are found in patients with the acute or subacute onset of symptoms of limbic encephalitis, peripheral nerve hyperexcitability, and neuromyotonia.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.