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Plasminogen Activator Inhibitor (PAI 1) Ag
Test Code36555
CPT Codes
85415
Preferred Specimen
1 mL frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL
Instructions
Refer to Quest Diagnostics Nichols Institute Directory of Services under Specimen Collection section, Coagulation Testing for further information on specimen processing.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 2 hours
Frozen -20° C: 30 days
Frozen -70° C: 1 year
Refrigerated: 2 hours
Frozen -20° C: 30 days
Frozen -70° C: 1 year
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received thawed • Received room temperature • Received refrigerated
Methodology
Enzyme Immunoassay (EIA)
Setup Schedule
Night
Report Available
Reports in 3 days.
Clinical Significance
Increased activity is associated with increased risk of arterial thrombosis, such as with unexplained premature myocardial infarction. As an acute phase reactant, the activity is increased after an acute event. Studies suggest PAI-1 may be a prognostic marker in early stage breast cancer.
