Test Code

CPT Codes
88184, 88185

Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume
1 mL

Other Acceptable Specimens
Whole blood or bone marrow collected in: Sodium heparin (green-top) tube

Submit green-top or EDTA whole blood. Ship blood/bone marrow at room temperature.

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • ACD Solution B (yellow-top) tube

Flow Cytometry (FC)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
A.M.; P.M. Sets up 7 days a week.

Clinical Significance
Patients with chronic lymphocytic leukemia have variable outcome. Some live with their disease for more than 25 years and some die within a few years. ZAP70 can predict patients who have aggressive disease and need aggressive therapy.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.