⁠⁠⁠⁠⁠⁠⁠Mycobacterium tuberculosis Complex, PCR, Culture and Smear, Respiratory

Test Code

14684

CPT Codes
87116, 87206, 87556

Includes

Mycobacteria, Culture, with Fluorochrome Smear
Mycobacterium tuberculosis Complex, PCR, Respiratory

An additional charge for Concentration (CPT code(s): 87015) will be added as appropriate.

Identification will be performed at an additional charge for each organism:
CPT code(s) 87118: Matrix Assisted Laser Desorption/Ionization-Time of Flight or
CPT code(s) 87153: AFB Sequencing

If TB is isolated for the first time or after three months after the first isolate from a patient, susceptibilities will be performed at an additional charge (CPT code(s): 87190 per drug).

Preferred Specimen

10 mL bronchial or tracheal lavage/wash, sputum or pleural fluid collected in a sterile leak-proof container

Patient Preparation
⁠⁠⁠⁠⁠⁠⁠Expectorated sputum: Instruct patient to gargle with water and cough deeply. Three separate early morning collections on at least three consecutive days are recommended.

Minimum Volume

2 mL

Instructions

Do not freeze samples.

See the alphabetical listing in the Microbiology section of Specimen Collection & Transport Guide for further instructions.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 5 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

24 hour pooled sputum • Swabs • Specimens received in alcohol, formalin, EDTA, lithium heparin or conventional blood culture bottles

Methodology
Continuous Monitoring Broth Culture System and Conventional Culture • Microscopic Exam with Fluorochrome Stain • Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Daily; Report available: 50-51 days

Clinical Significance

There are more than 70 species of Mycobacteria of which the primary pathogen is M. tuberculosis. Tuberculosis is a chronic, granulomatous disease caused by M. tuberculosis. Identification, and, if appropriate, antibiotic sensitivity, is required to initiate necessary therapy.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.