Tysabri® Antibody Test

Test Code
19215


CPT Codes
83516

Preferred Specimen
2 mL serum


Minimum Volume
0.5 mL


Instructions
Please label each specimen tube with two forms of patient identification. These forms of identification
must also appear on the requisition form.

Collect whole blood in a red top tube (no-gel) or a serum separator tube, let it clot for at least 30 minutes
at room temperature and centrifuge within 1 hour of collection. Transfer the serum to a plastic screwcap
vial for transport to the laboratory.


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 6 months


Methodology
Enzyme Linked Immunosorbent Assay (ELISA)

Setup Schedule
Set up: Fri; Report available: 7-10 days


Clinical Significance
Antibodies against natalizumab (Tysabri) are found in 4.5% to 14.1% of natalizumab-treated multiple sclerosis patients.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.