Antimicrobial Susceptibility, Nocardia/Aerobic Actinomycetes, MIC

Test Code
90396


CPT Codes
87186

Includes
Amikacin, Amoxicillin/Clavulanate, Ceftriaxone, Ciprofloxacin, Clarithromycin, Doxycycline, Imipenem, Linezolid, Minocycline, Moxifloxacin, Tobramycin, Trimethoprim/Sulfamethoxazole


Preferred Specimen
Pure culture of Nocardia spp., or other aerobic actinomycetes safely contained (including but not limited to: Rhodococcus, Gordonia, Tsukamurella, Streptomyces)


Instructions
Identification of the isolate is required


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Determined by viability
Refrigerated: Determined by viability
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Mixed cultures or organisms not considered nocardia or aerobic actinomycetes • Raw specimens • Frozen isolates • Isolates overgrown with bacteria, yeast, fungi


Methodology
Broth Microdilution

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule
Set up: Mon, Tue, Fri; Report available: 18-19 days


Clinical Significance
Rapidly growing mycobacteria and Nocardia/aerobic actinomycetes can cause a variety of serious infections, particularly in immunocompromised patients. Resistance, toxicity, intolerance, and therapeutic failures may occur with traditional empiric treatment with drugs of choice. Antimicrobial susceptibility testing, especially with newer agents, may help to guide appropriate therapeutic choices.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.