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Myelin Antibody (IgG), IFA
Test Code4639X
CPT Codes
86255
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.3 mL
Instructions
Serum specimens should be collected under aseptic condition. Hemolysis should be avoided through prompt separation of the serum from the clot.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Specimens with visible particulate matter • Serum separator tube (SST)
Methodology
Indirect Immunofluorescence
FDA Status
This test was performed using a kit that has not been approved or cleared by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Setup Schedule
A.M. Sets up 1 day a week.
Clinical Significance
Antibodies against myelin are found in multiple sclerosis and other neurological diseases. However, the diagnostic value of this serum antibody is controversial, as high titers in healthy subjects can also be detected. Antibodies against myelin-associated glycoproteins are present at times with Guillain-Barre syndrome.
