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Porphyrins, Fractionated, Quantitative, Random Urine
Test Code36592
CPT Codes
84120
Includes
Coproporphyrin I, Coproporphyrin III, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Uroporphyrin I, Uroporphyrin III, Total Porphyrins
Preferred Specimen
2 mL random urine in 5 g sodium carbonate container or no preservative container - protected from light
Minimum Volume
1.5 mL
Other Acceptable Specimens
Catheterized urine • First void clean catch urine • Random clean catch urine collected with no preservative
Instructions
Random urine collected with 5 grams of sodium carbonate, refrigerated and protected from light during collection is preferred.
Collection with no preservative is acceptable, if properly refrigerated and light protected.
Collection with no preservative is acceptable, if properly refrigerated and light protected.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Samples not protected from light • Samples with a pH <4.0
Methodology
High Performance Liquid Chromatography (HPLC)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
A.M.; P.M. Sets up 5 days a week.
Clinical Significance
Clinical use is to diagnose porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria.
