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Rubella Antibodies (IgG, IgM) Diagnostic
Test Code37673
CPT Codes
86762 (x2)
Preferred Specimen
1 mL serum
Minimum Volume
0.7 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report Available: 1-3 days
Limitations
False-positives may be found in newborns from mothers. IgM may persist after infection is treated.
Clinical Significance
Rubella (German Measles) is a common and usually benign viral infection of children. IgM antibody is detectable 11-25 days after the onset of exanthem, in most individuals 15-25 days after vaccination, and in 90-97% of infants with congenital rubella between 2 weeks and 3 months after birth. Acute and convalescent IgG titers may be interpreted to identify a >30% rise in the antibody index. A positive IgG antibody indicates successful immunization or past exposure.