Bupropion and Metabolite, Serum/Plasma

Test Code

8592

CPT Codes
80338 (HCPCS: G0480)

Includes

Bupropion and Hydroxybupropion

Preferred Specimen

1 mL frozen serum collected in a red-top tube (no gel)

Patient Preparation
Collect as a trough prior to next dose

Minimum Volume

0.4 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube

Instructions

Collect serum and remove from cells

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • Received refrigerated • Gel barrier/Serum Separator Tube (SST®)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

P.M. Sets up 3 days a week.

Report Available

Reports in 2 days.

Clinical Significance

Bupropion is an antidepressant for treating mental depression. Monitoring its level is important to optimize therapy, to avoid toxicity and to assure compliance.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.