Pharmacogenomics Panel with Coriell Life Sciences (CLS) Report

Test Code

14271

CPT Codes
81418<br><strong>This test is not available for New York patient testing.</strong>

Preferred Specimen

5 mL whole blood collected in an EDTA (lavender-top) tube

Patient Preparation
Buccal: Do NOT eat, drink, smoke or chew gum for 30 minutes before collection. Do NOT touch swab or allow contact with any other object.
Saliva: Do NOT eat, drink, smoke or chew gum for 30 minutes before collection. Do NOT remove the plastic film from the funnel lid.

Minimum Volume

2 mL whole blood • 3 mL salvia • 1 swab

Other Acceptable Specimens

Whole blood collected in: ACD (yellow-top) tube • 4 mL saliva collected in an OGD-500 OR OGD-600 Oragene-Dx collection kit up to the "FILL TO" line on the device • 1 buccal swab collected in an OCD100A, ORAcollect-Dx DNA collection kit

Transport Temperature

Room temperature

Specimen Stability

Whole blood
Room temperature: 30 days
Refrigerated: 8 days
Frozen: Unacceptable

Saliva/buccal swab
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis

Methodology
Microarray

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon, Tues, Thurs, Sat; Report available: 8-24 days

Clinical Significance

Genetics can play a significant role in the selection of certain medications. For instance, individuals may metabolize medications too fast or too slow. This test analyzes genes of known pharmacogenomic value allowing clinicians to gain valuable insight into an individual's response to and adverse effects from medications with known gene-drug interactions. In partnership with Coriell Life Sciences, this test offers an enhanced report providing medication guidance and clinical annotation based on the genetic results provided by Quest Diagnostics.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.