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Drug Monitoring Assess Panel, Volatiles, Urine
Test Code11877
CPT Codes
80320 (HCPCS: G0480)
Includes
Acetone
Ethanol
Isopropanol
Methanol
Ethanol
Isopropanol
Methanol
Preferred Specimen
2 mL random urine in a plastic urine container
Minimum Volume
1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 30 days
Refrigerated: 21 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Preserved urine
Methodology
Chromatography
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes
Setup Schedule
Set up Daily; Report available: 1-2 days
Clinical Significance
Ethanol is the most commonly abused substance whose primary effect on the central nervous system varies with blood concentration. Not all individuals experience the same effects at a given blood level. Additionally, other central nervous system depressants can have an additive effect when taken in combination with ethanol. Approximately 5% of ethanol is excreted unchanged in urine. A positive urine ethanol result may suggest recent ethanol exposure and/or consumption; however, in diabetic patients with a urinary tract infection, ethanol is commonly present in urine as a result of glucose fermentation by yeast in the urine. When fermentation is not suspected, and urine ethanol is adjusted by a sample's creatinine concentration, urine ethanol may be used to estimate blood ethanol concentrations, as urine ethanol concentrations are approximately 130% of blood concentrations, if the patient is in the elimination phase. Caution should be exercised with interpretation of urine ethanol results; it is not recommended that a clinical decision be based solely on a urine ethanol result as there are several different scenarios that may have yielded the result.