Disaccharidases

Test Code

19701

CPT Codes
82657 (x4)<br><strong>This test is not available for New York patient testing. For New York patient testing use test code 13689.</strong>

Includes

Lactase, Maltase, Palatinase, Sucrase

Preferred Specimen

5 mg frozen small bowel biopsy collected in a 2 mL cryovial polypropylene screw-cap tube

Minimum Volume

2 mg

Instructions

Place 5 mg small bowel biopsy on the interior surface of a 2 mL polypropylene screw-cap cryovial or small polypropylene collection tube. Freeze within 2 hours of collection at -20° C.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 31 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Samples frozen later than 2 hours post collection • Samples received in urine containers • Samples immersed in a colorless fluid (i.e., water, formalin, saline, etc.) • Samples placed on gauze, filter paper or any other type of support media

Methodology
Spectrophotometry (SP)

Setup Schedule

Set up: Sun-Fri; Report available: 1-3 days

Clinical Significance

Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.