A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Sirolimus, LC/MS/MS (NY)
Test Code13608
CPT Codes
80195 <br><strong>This test is for New York patient testing only. For non-New York patient testing use test code 36712.</strong>
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube
Patient Preparation
Collect specimen 1 hour prior to next dose (12 hour trough)
Minimum Volume
1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimen
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Clinical Significance
Sirolimus is an immunosuppressant drug used to prevent organ graft rejection. Therapeutic drug monitoring is used to optimize dose and avoid toxicity. Peak concentrations are reached in 2 hours following oral administration. Elimination half-life in males is approximately 72 hours; in females approximately 61 hours.