Extended Myositis Panel

Test Code

39933

CPT Codes
**Restricted Client Code**

Includes

SSA-52 (Ro52)(ENA)Ab, IgG
SSA-60 (Ro60)(ENA)Ab, IgG
Smith/RNP (ENA) Ab, IgG
Jo-1 Ab, IgG
PL-12 Antibody
PL-7 Antibody
EJ Antibody
OJ Antibody
SRP Ab
Ku Antibody
PM/Scl 100 Antibody, IgG
Fibrillarin(U3 RNP)Ab,IgG
Mi-2 Antibody
P155/140 Antibody
TIF-1 gamma (155 kDa) Ab
SAE1 Ab
MDA5 (CADM-140) Ab
NXP2 Ab

Preferred Specimen

1 mL serum (x3)

Minimum Volume

0.5 mL aliquots (x3)

Instructions

Separate from cells ASAP or within 2 hours of collection. Transfer three 1 mL serum aliquots to ARUP standard transport tubes.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 1 month

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Grossly lipemic • Icteric • Heat-treated • Contaminated specimens

Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay • Qualitative Immunoprecipitation • Semi-Quantitative Multiplex Bead Assay • Qualitative Immunoblot

FDA Status
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Setup Schedule

Set up: Daily; Report available: 7-18 days

Clinical Significance

May be useful for differential evaluation of polymyositis, dermatomyositis, necrotizing autoimmune myopathy, or overlap syndromes associated with connective tissue disease.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.