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GASTRIC PARIETAL CELL ANTIBODY, IGG
Test CodeLAB4546
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Received room temperature
Methodology
Immunoassay (IA)
Setup Schedule
a.m. Tues, Thurs, Sat
Report Available
3-6 days
Clinical Significance
Gastric Parietal Cell Antibodies are found in 90% of patients with pernicious anemia. They are also found in autoimmune chronic atrophic gastritis preceding pernicious anemia. The antigenic target is the H+/K+ ATPase gastric proton pump responsible for parietal cell acid generation in the stomach.
