CHROMOSOME ANALYSIS, CONSTITUTIONAL BLOOD, WITH REFLEX TO GENOMIC MICROARRAY

Test Code

LAB2005763

Includes

If Chromosome analysis is normal, then Chromosomal Microarray, Postnatal, ClariSure® Oligo-SNP will be performed at an additional charge (CPT code(s): 81229)

Preferred Specimen

10 mL whole blood collected in a sodium heparin (green-top) tube

Minimum Volume

5 mL

Other Acceptable Specimens

Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube

Transport Container

Sodium heparin (green-top) tube

Transport Temperature

Room temperature

Specimen Stability

Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.

Methodology
Culture • Karyotype • Microscopy

Reflex: Oligo-SNP Array

Setup Schedule

Daily

Report Available

Chromosome: 10 days (if needed, Array: 7 days later)

Clinical Significance

Chromosome analysis can be used to help determine genetic causes of intellectual disability, developmental delay, congenital anomalies, infertility, miscarriage, stillbirth, and ambiguous genitalia. Chromosome analysis does not rule out cryptic or submicroscopic chromosome abnormalities. If this analysis is normal, microarray will be performed for the detection of submicroscopic deletions and duplications and long continuous regions of homozygosity.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.