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Sensory Neuropathy Antibody Panel (Ganglioside)
Test Code90124
Includes
Ganglioside GD1b Antibody (IgG), EIA; Ganglioside GD1b Antibody (IgM), EIA; Ganglioside GQ1b Antibody (IgG), EIA
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.6 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 21 days
Refrigerated: 7 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature
Methodology
Immunoassay (IA)
Setup Schedule
See individual assays
Clinical Significance
Gangliosides GD1b IgG is associated with acute motor and sensory axonal neuropathy with associated cerebellar ataxia and ataxic presentations of Guillain-Barré Syndrome. GQ1b IgG may be associated with Miller-Fisher Syndrome. GQ1b IgM antibody is associated with chronic sensory ataxic neuropathy.
