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Sickle Cell Screen
Test Code825
Preferred Specimen
4 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Instructions
Note: This test is not appropriate for patients less than 6 months old due to interference by Hemoglobin
F. In these cases, it is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered.
Maintain specimen at room temperature. Do not centrifuge.
F. In these cases, it is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered.
Maintain specimen at room temperature. Do not centrifuge.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: Unacceptable
Refrigerated: 14 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Clotted
Methodology
Solubility
Setup Schedule
Sets up 7 days a week.
Clinical Significance
This is a screening test to determine the presence of sickling hemoglobins. (e.g. hemoglobin-s, hemoglobin c-Harlem). It is important to detect Hb-S in order to determine which individuals are at risk of crisis when exposed to prolonged anoxia such as may occur during surgery, athletic programs or high altitude conditions.