A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Posaconazole
Test CodePOSALC/MS/MS
Quest Code
94010
CPT Codes
80187<br><strong>This test code is for non-New York patient testing. For New York patient testing, see test code 13235.</strong>
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes (SST) • Other body fluids
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Sets up 3 days a week.
Reference Range
after 7 days of treatment
Target for prophylaxis purpose | trough level >0.7 mcg/mL |
Target for salvage treatment | trough level >1.25 mcg/mL |
Clinical Significance
The antifungal drug posaconazole is indicated for prophylaxis of invasive aspergillus and candida infections in severely immunocompromised patients. It may also be used in the treatment of oropharyngeal candidiasis refractory to itraconazole and fluconazole. The chronic nature of fungal infections demands constant monitoring of posaconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted.
Performing Laboratory
MedFusion |
2501 South State Hwy 121, Suite 1100 |
Lewisville, TX 75067-8188 |