Advanced Lipid Panel, Cardio IQ®

Order as ESOT to QNI - Test Code: 92145
Customer Service must enter AOE Information in Quest Quanum in order for test to be resulted.

Enter all applicable fields:
         Test Name: Advanced Lipid Panel, Cardio IQ®
         Reference Lab: QNI
         Test Code: 92145
         Shipping Temp: REFRIGERATED
         Specimen Type: 4 ML SERUM
         TAT: 4 DAYS
         CPT Code: 82465, 83718, 84478, 83704, 82172, 83695
         Cost: _
         Additional Comments: _
         FDA Approved Test:  YES_    NO_    LDT_
         Medical Director/Pathologist: approved by _
         Billing Completed by_    Date_   Time_

Test Code
ESOT - 92145 - QNI

Quest Code

Alias/See Also

CPT Codes
82465, 83718, 84478, 83704, 82172, 83695

Cardio IQ® Cholesterol, Total
Cardio IQ® HDL Cholesterol
Cardio IQ® Triglycerides
Cardio IQ® Non-HDL and Calculated Components
Cardio IQ® Lipoprotein Fractionation, Ion Mobility
Cardio IQ® Apolipoprotein B
Cardio IQ® Lipoprotein (a)

If Triglyceride is >400 mg/dL, then Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721).

Preferred Specimen
4 mL serum

Patient Preparation
Fasting is not required prior to collection of a lipid panel.
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.

Minimum Volume
2 mL

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Moderate to grossly icteric • Grossly lipemic

Enzymatic • Fixed Rate Nephelometry • Immunoturbidometric • Ion Mobility • Spectrophotometry (SP) • Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Night Sets up 5 days a week.

Reference Range
See Laboratory Report

Clinical Significance
The advanced lipid profile provides a more comprehensive assessment of dyslipidemia and cardiovascular risk than standard lipid panel measurements. Standard lipid panels measure total cholesterol, HDL-C, and triglycerides, and a calculated LDL-C, but do not capture all of the complexity of dyslipidemia and associated CVD risk. For a substantial number of individuals, lipoprotein measures such as LDL particle number, ApoB and Lp(a) add to the predictive power of standard lipid assessment of CVD risk. The advanced lipid profile combines a standard lipid panel with 3 additional tests: lipoprotein subfraction assessment by ion mobility of LDL particle number and LDL and HDL particle subclass concentrations, the ApoB test, and the Lp(a) test.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.