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Copper, 24-Hour Urine
Test Code365
CPT Codes
82525
Includes
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
7 mL aliquot of a well mixed 24 hour urine collected in acid washed or metal free container
Minimum Volume
3 mL
Instructions
Collect without preservative and transport in a plastic, acid washed, metal free container. Record total volume on specimen container and on test requisition. Random urine is not acceptable. To avoid contamination, do not measure 24-hour volume.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Fecal contamination
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
Setup Schedule
Sun, Wed, Fri
Report Available
1 to 4 Day(s)
Clinical Significance
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Urinary copper concentrations are also useful to monitor patients on chealation therapy.
