Antiphospholipid Syndrome Evaluation Panel with Reflexes

Test Code
91248


CPT Codes
85613, 86146 (x3), 86147 (x3), 86148 (x3)

Includes
Phosphatidylserine Antibodies (IgA)
Phosphatidylserine Antibodies (IgG)
Phosphatidylserine Antibodies (IgM)
dRVVT Screen w/rfl dRVVT Confirm and dRVVT1:1 Mix
Cardiolipin Ab (IgG)
Cardiolipin Ab (IgM)
Cardiolipin Ab (IgA)
B2 Glycoprotein I (IgG) Ab
B2 Glycoprotein I (IgM) Ab
B2 Glycoprotein I (IgA) Ab

If dRVVT screen is prolonged (>45 seconds), the dRVVT Confirmation will be performed at an additional charge. If dRVVT Confirm is positive, a dRVVT 1:1 dilution will be performed at an additional charge.


Preferred Specimen
1 mL frozen platelet-poor citrated plasma collected in each of three separate sodium citrate (light blue-top) tubes


Minimum Volume
0.5 mL (x3)


Transport Temperature
Frozen


Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Thawed plasma


Methodology
Immunoassay • Photo-optical Clot Detection • Calculation

Setup Schedule
Mon-Sat


Report Available
4 to 6 Day(s)


Clinical Significance
The antiphospholipid antibody syndrome (APS) is a clinical-pathologic correlation that includes a clinical event (e.g. thrombosis, pregnancy loss, thrombocytopenia) and persistent positive antiphospholipid antibodies and/or a lupus anticoagulant.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.