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Barbiturates, Quantitative Confirmation, Serum
Test Code7377
CPT Codes
80345 (HCPCS: G0480)
Includes
Amobarbital, Butabarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 14 days
Refrigerated: 7 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Mon-Fri
Report Available
3 to 4 Day(s)
Clinical Significance
Extensively used for hypnotics, sedatives and anesthetics. Readily absorbed from the stomach. Duration of action of barbiturates, in therapeutic doses varies from: 8-16 hours (long acting e.g., phenobarbital); 4-8 hours (Intermediate acting e.g, amobarbital); 3-6 hours (short acting e.g., pentobarbital). Barbiturates may enhance other CNS depressants, such as ethanol, morphine derivatives, tranquilzers, and resperine.
