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Vitamin E (Tocopherol)
Test Code931
CPT Codes
84446
Includes
Alpha-Tocopherol and Beta-Gamma-Tocopherol
Preferred Specimen
2 mL serum protected from light
Patient Preparation
Overnight fasting is required
Minimum Volume
0.7 mL
Instructions
Separate from cells as soon as possible after clotting. Send serum in an amber tube. If an amber tube is not available, wrap tube in aluminum foil to protect from light.
Transport Container
Amber tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Not light Protected • Plasma • Contaminated • Grossly-hemolyzed or heavily-lipemic sera
Methodology
High Performance Liquid Chromatography (HPLC)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Mon-Sat
Report Available
2 to 3 Day(s)
Clinical Significance
Deficiency of vitamin E may cause extensive neuropathy in young children and, in addition, is suspect as a possible cause of motor and sensory neuropathy in older children and in adults. One likely cause of vitamin E deficiency is intestinal malabsorption, resulting from bowel disease, pancreatic disease, or chronic cholestasis. Other causes of malabsorption of vitamin E include celiac disease, cystic fibrosis, and intestinal lymphangiectasia.