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Histone Antibodies [37056]
Test CodeS52096
CPT Codes
83516
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred.
Minimum Volume
0.3 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 24 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis
Methodology
Enzyme Immunoassay (EIA)
Setup Schedule
Tues, Thurs, Sat
Report Available
2 to 3 days
Clinical Significance
Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.
