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Alpha-1-Antitrypsin, Quantitative
Test Code1513
CPT Codes
82103
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Centrifuge and transfer serum specimens to clean, plastic, screw-capped vial(s)
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 90 days
Refrigerated: 7 days
Frozen: 90 days
Methodology
Immunoturbidimetric Assay
Setup Schedule
Set up: Tues-Sat; Report available: 1-3 days
Clinical Significance
Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, aat phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.