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Helicobacter pylori Antigen, EIA, Stool
Test Code34838
CPT Codes
87338
Preferred Specimen
Minimum: 0.5 mL or grams of stool collected in a plastic, leak-proof container, no preservatives
Patient Preparation
For initial diagnostic purposes no special patient preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained.
To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days post therapy is indicative of treatment failure.
This test is cleared for use with specimens from pediatric patients.
Instructions
Collect 0.5 mL or 0.5 grams of semi-solid stool or, 20 mm diameter solid stool and transfer to properly labeled plastic, leak-proof container. Do not place stool in preservative, transport media or swab.
Watery, diarrheal stool is not acceptable.
Watery, diarrheal stool is not acceptable.
Transport Temperature
Frozen
Specimen Stability
Refrigerated: 72 hours
Frozen: 30 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Watery, diarrheal stool • Stool in preservative • Transport media or swab
Methodology
Immunoassay (IA)
Setup Schedule
Sun-Sat
Report Available
1 to 4 Day(s)
Clinical Significance
Colonization with H. pylori is associated with increased risk of patients developing gastritis, peptic ulcer disease, and gastric adenocarcinoma. Stool antigen testing provides a sensitive measure of infection including during and after treatment.