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Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

Test Code
11173


CPT Codes
86200

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia • Plasma


Methodology
Immunoassay (IA)

Setup Schedule
Sun, Tue-Sat


Report Available
1 to 3 Day(s)


Limitations
The presence of immune complexes may cause false-positive results due to increased non-specific binding.


Clinical Significance
A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from other patients than either the perinuclear autoantibody test or the test for rheumatoid factor. Approximately 70% of patients with Rheumatoid Arthritis are positive for Anti-CCP IgG, while only about 2% of random blood donors and disease controls subjects are positive.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.