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Hu Antibody Screen with Reflex to Titer and Western Blot
Test Code37053
CPT Codes
86255
Includes
If Hu Antibody Screen, IFA is positive, then Hu Antibody, WB will be performed at an additional charge (CPT code(s): 84181).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
Preferred Specimen
0.5 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.2 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Methodology
Immunofluorescence Assay (IFA) • Western Blot (WB)
Setup Schedule
Mon, Wed, Fri
Report Available
4 to 4 Day(s)
Clinical Significance
Paraneoplastic Syndrome involves non-metastatic systemic effects that accompany malignant disease. Antineuronal Nuclear Antibody (Anti-Hu) is found in 5-10% of patients with small cell carcinoma of the lung. Anti-Hu is associated with subacute syndrome of encephalomyeloradiculopathy, sensory neuropathy, and autoimmune neuropathy, predominantly affecting the gastrointestinal tract.
