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dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix

Test Code
15780


CPT Codes
85613

Includes
If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).


Preferred Specimen
2 mL frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube


Minimum Volume
1 mL


Instructions
Platelet-Poor Plasma: Centrifuge light blue-top tube 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.

Note: the presence of direct oral anticoagulants may interfere with testing.


Transport Temperature
Frozen


Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 90 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis


Methodology
Clot Detection

Setup Schedule
Mon-Sat


Clinical Significance
The dilute Russell Viper Venom time integrated test is a sensitive method for the detection of Lupus Anticoagulants (LA). LA are autoantibodies that target protein-phospholipid complexes and are found in a variety of clinical conditions. In some patients, a confirmed positive result is associated with an increased thrombotic risk, and is often found in women who have recurrent fetal loss.

Note: The presence of direct anticoagulants may interfere with testing.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.