CENTROMERE ANTIBODY

Test Code

LAB1173

Quest Code

16088

CPT Codes
86235

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology
Immunoassay (IA)

Setup Schedule

a.m. Mon-Fri

Report Available

1-4 days

Limitations

As many as 15% of health controls may have low or slightly elevated antibody levels.

Reference Range

<1.0 AI Negative

Clinical Significance

Centromere B Antibody is diagnostic for the form of scleroderma known as CREST (calcinosis, Raynaud's phenomenon, esophageal immotility, sclerodactyly, and telangiectasia).

Performing Laboratory

Quest Diagnostics-Lenexa

10101 Renner Blvd

Lenexa, KS 66219-9752

Last Updated: November 3, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.